Is a species of amphibian in the Phyllomedusidae family, measuring up to 59 mm for males and 77 mm for females.
Its dorsal side varies from leaf green to dark green. Its flanks are dark blue, violet or brown, with yellow or cream vertical slashes. Its limbs are tinted blue or orange. Its ventral side is white. Their eyes are globular, red and have vertical pupils.
The skin on her back and belly is smooth. Juveniles can change color from green during the day to purplish or reddish-brown at night. Their eyes are more yellow than red, and their flanks are devoid of clear markings.
Its red eyes with vertical pupils are the origin of its name. Its habits are nocturnal. Its predators are nocturnal birds, bats and snakes, which eat it despite the presence of toxic substances in its skin.
Red-eyed tree frog embryos have demonstrated phenotypic plasticity, enabling them to hatch early in response to danger to protect themselves. Experiments have shown that when attacked by snakes (Leptodeira), the eggs hatch quickly, enabling the tadpoles to escape and reach the water, where their chances of survival are higher.